Kirk I. Erickson, PhD

Assistant Professor, Psychology


3107 Sennott Square
F: 412-624-4428
Website >


Neuroimaging and cognitive studies of age and health.

Research Summary

My research has focused on understanding the changes in various aspects of cognition, and the supporting brain structure and function, across the lifespan. For example, I have studied the manner in which executive control processes (e.g. planning, scheduling, working memory, inhibition, task coordination) change from early to late adulthood. In this research I have reported substantial individual differences in the rate of change. Some adults experience rapid changes while others show more gradual changes or very little change in function with advancing age. This demonstrates that although cognitive decline and brain atrophy is common in old age, it is far from being inevitable.

Along these lines, my research is also involved in examining the factors that promote successful aging. For example, environmental factors such as vitamin supplementation, physical activity, and hormone replacement influence the trajectory of cognitive decline. Participation in moderate amounts of physical activity can significantly improve cognitive and brain function in older adults. In addition, only 6-months of aerobic exercise was enough to restore lost volume in the prefrontal and temporal cortices.

Genetic factors also play a role in the trajectory of cognitive and brain deterioration in old age. In one recent study we have found that a genetic polymorphism in the BDNF gene contributes to the rate of cognitive decline in old age. We are currently examining how genetic predispositions interact with environmental factors (e.g. physical activity) to influence neurocognitive function in old age.

In short, I take a brain plasticity perspective in the study of age-related patterns of deterioration. My research, from both cross-sectional and randomized intervention studies, has demonstrated that the older adult brain retains its capacity for plasticity.

To examine these research questions, my colleagues and I bring to bear methodologies ranging from reaction time and accuracy, mathematical modeling, and neuroimaging techniques such as functional and anatomical MRI.


Casanova, R, Hayasaka, Saldana, S, Bryan, RN, Demos, KE, Desiderio, L, Erickson, KI, Espeland, MA, Nasrallah, IM, Wadden, T, Laurienti, P.  (2016).  Relative differences in resting-state brain connectivity associated with long-term intensive lifestyle intervention. Psychoneuroendocrinology, 74: 231-239. Casanova2016.pdf
Chaddock-Heyman, L, Erickson, KI, Chappell, MA, Kienzler, C, Johnson, CL, Knecht, A, Drollette, ES, Raine, LB, Scudder, MR, Kao, SC, Hillman, CH, Kramer, AF. (2016). Aerobic fitness is associated with greater hippocampal cerebral blood flow in children.  Developmental Cognitive Neuroscience, 20: 52-8. ChaddockHeyman2016.pdf
Donofry, SD, Roecklein, KA, Wildes, JE, Miller, MA, & Erickson, KI (2016). Alterations in Emotion Generation and Regulation Neurocircuitry in Depression and Eating Disorders: A Comparative Review of Structural and Functional Neuroimaging Studies. Neuroscience and Biobehavioral Reviews, 68: 911-927. Donofry2016.pdf
Drollette, ES, Scudder, MP, Raine, LB, Moore, RD, Pontifex. MB, Erickson, KI, Hillman, CH. (2016) The sexual dimorphic association of cardiorespiratory fitness to working memory in children. Developmental Sciences, 19: 90-108.Drollette2016.pdf
Espeland, MA, Erickson, KI, Neiberg, RH, Jakicic, JM, Wadden, TA, Wing, RR, Desiderio, L, Erus, G, Hsieh, MK, Davatzikos, C, Maschak-Carey, BJ, Laurienti, PJ, Demos-McDermott, K, Bryan, RN.  (2016).  Brain and white matter hyperintensity volumes after ten years of random assignment to lifestyle intervention.  Diabetes Care, 39: 764-71. Espeland2016.pdf
Gildengers, AG, Butters, MA, Albert, SM, Anderson, SJ, Dew, MA, Erickson, KI, Garand, L, Karp, JF, Lockovich, MH, Morse, J, Reynolds, CF. (2016).  The design and implementation of an intervention development study: Retaining Cognition While Avoiding Late-Life Depression.  American Journal of Geriatric Psychiatry, 24: 444-54. Gildengers2016.pdf
Jackson, PA, Pialoux, V, Corbett, D, Drogos, L, Erickson, KI, Eskes, GA, Poulin, MJ. Promoting brain health through exercise and diet in older adults: a physiological perspective (2016).  Journal of Physiology, 594: 4485-98. Jackson2016.pdf
Jorgensen, L, Palmer, C, Pratt, S, Erickson, KI, Moncrieff, D.  (2016).  The effect of decreased audibility on MMSE performance: a measure commonly used for diagnosing dementia.  Journal of the American Academy of Audiology, 27: 311-323. Jorgensen2016.pdf
Lukach, AJ, Jedrziewski, MK, Grove, GA, Mechanic-Hamilton, DJ, Williams, SS, Wollam, ME, Erickson, KI. (2016). Rhythm Experience and Africana Culture Trial (REACT!): A culturally salient intervention to promote neurocognitive health, mood, and well-being in older African Americans. Contemp Clin Trials, 48: 41-5. Lukach2016.pdf
Erickson, KI, McAuley, E, Kramer, AF. (2015).  Higher cardiorespiratory fitness levels are associated with greater hippocampal volume in breast cancer survivors.  Frontiers in Human Neuroscience, 9:465. Chaddock-Heyman2015b.pdf
Erickson, KI, Hillman, CH, Kramer, AF. (2015).  Physical Activity, Brain, and Cognition.  Current Opinion in Behavioral Sciences, 4: 27-32.