Cell and Molecular
Cellular and molecular mechanisms of neurodegeneration and neuroprotection.
Growth factors and sensory neuron function in pain and nerve injury.
Synaptic integration and plasticity in hippocampal area CA3.
Plasticity in developing and adult neocortex.
Mitochondria in neurodegeneration
Cell signaling, mitochondria and autophagy regulation in genetic models of Parkinson's disease.
Functional consequences of altered connectivity in schizophrenia; the early secretory pathway's role in neurodevelopment and synaptogenesis
Developing a better understanding of the molecular mechanisms by which synaptic vesicles dynamically load, retain and release neurotransmitters such as dopamine and how these processes contribute to neuropsychiatric illnesses
Mechanisms of neurodegeneration and neuroprotection in Parkinson's and Huntington's diseases.
Mechanism(s) of alcohol action.
Synaptic computation and neuromodulation in catecholaminergic neurons
Cellular and circuitry mechanisms underlying drug addiction and sleep regulation of reward.
Regulation of GABAergic inhibition in development and mental disorders
Biophysics, pharmacology, and regulation of glutamate receptors.
Regulation of actin network organization at cell-cell contacts.
Circadian rhythms of psychiatric disorders
The molecular basis of psychiatric diseases.
Regulation and modulation of presynaptic ion channels and transmitter release in healthy and diseased synapses.
Molecular mechanisms of neurodegenerative diseases.
Signal transduction pathways in glioma growth, molecular markers of glioma prognosis.
The goal of our research is to functionally dissect the neural circuits that underlie pain and itch.
Fundamental and clinical research on cellular and molecular mechanisms of retinal degeneration and development of treatments for currently incurable blinding diseases
Cellular and molecular mechanisms of physiological and pathophysiological synaptic plasticity
Neural circuits and behavior
Cell and molecular biology of dopamine transporter
Cellular mechanisms for learning and memory and their role in auditory processing.
Gene and stem cell therapy in brain ischemia/membrane protein structure by NMR.