Cell and Molecular
Cellular and molecular signaling processes in neurodegeneration.
Growth factors and sensory neuron function in pain and nerve injury.
Synaptic integration and plasticity in hippocampal area CA3.
Plasticity in developing and adult neocortex.
Mitochondria in neurodegeneration
Cell signaling, mitochondria and autophagy regulation in genetic models of Parkinson's disease.
Functional consequences of altered connectivity in schizophrenia; the early secretory pathway's role in neurodevelopment and synaptogenesis
Mechanisms of neurodegeneration and neuroprotection in Parkinson's and Huntington's diseases.
Mechanism(s) of alcohol action.
Synaptic computation and neuromodulation in catecholaminergic neurons
Cellular and circuitry mechanisms underlying drug addiction and sleep regulation of reward.
Regulation of GABAergic inhibition in development and mental disorders
Biophysics, pharmacology, and regulation of glutamate receptors.
Regulation of actin network organization at cell-cell contacts.
Control of transmitter release by electrical and biochemical signaling.
Development, maturation and function of the auditory and somatosensory systems.
The molecular basis of psychiatric diseases.
Regulation and modulation of presynaptic ion channels and transmitter release in healthy and diseased synapses.
Molecular mechanisms of neurodegenerative diseases.
Signal transduction pathways in glioma growth, molecular markers of glioma prognosis.
Molecular and cellular basis of opioid drug addiction.
The goal of our research is to functionally dissect the neural circuits that underlie pain and itch.
Neural circuits and behavior
Cell and molecular biology of dopamine transporter
Regenerative medicine approaches to protecting and repairing the retina and the optic nerve.
Cellular and molecular neuroscience; cellular and molecular regulation of monoamine transporters.
Cellular mechanisms for learning and memory and their role in auditory processing.
Gene and stem cell therapy in brain ischemia/membrane protein structure by NMR.