Development / Plasticity / Repair

Growth factors and sensory neuron function in pain and nerve injury.
Cellular and molecular mechanisms of central and peripheral nervous system development and plasticity.
Mechanisms of post-traumatic memory deficits, models of traumatic brain injury, and functional outcomes.
Cellular and circuitry mechanisms underlying pathological neural plasticity
Neuroimaging and cognitive studies of age and health.
Functional consequences of altered connectivity in schizophrenia; the early secretory pathway's role in neurodevelopment and synaptogenesis
Cellular and molecular signaling processes important for central nervous system myelination and myelin repair.
Regulation of GABAergic inhibition in development and mental disorders
Development and plasticity of inhibitory circuits.
Development, plasticity and pain processing in sensory neurons and in the spinal dorsal horn.
Neurite outgrowth and synaptogenesis.
Motoneuron development and spinal cord patterning.
CNS stem cells.
Development, maturation and function of the auditory and somatosensory systems.
Regulation and modulation of presynaptic ion channels and transmitter release in healthy and diseased synapses.
Genetic analysis of vertebrate CNS development.
Contributions of cortical microcircuit properties to information processing and coding in the olfactory system.
Cellular transplants for spinal cord repair. Development of combinatorial spinal cord repair strategies.
The goal of our research is to functionally dissect the neural circuits that underlie pain and itch.
Theoretical and computational modeling of dynamics in neuronal networks.
Ultrastructure and the chemical nature of the tripartite synapse
Regenerative medicine approaches to protecting and repairing the retina and the optic nerve.
Ion transporters in neurological diseases.
Behavioral, biochemical, and physiological analysis of learning and memory.
The impact of gender and changes in neurochemistry on rehabilitation and treatment outcomes after traumatic brain injury (TBI).