Neural circuits implicated in the development, pathophysiology, and treatment of schizophrenia and other major psychiatric disorders
Employ multimodal imaging research techniques, including high density (hd)-EEG during sleep and wakefulness, Transcranial Magnetic Stimulation (TMS), structural and functional Magnetic Resonance Imaging (MRI), and Magnetic Resonance Spectroscopy Imaging (MRSI) in healthy and psychiatric populations to characterize the neurobiology and related cognitive dysfunctions of major psychiatric disorders, including obsessive compulsive, bipolar disorder, and schizophrenia.
Identify novel treatment targets and approaches, including neuromodulatory interventions for psychotic and other major psychiatric disorders
Donati FL, Kaskie R, Reis CC, D'Agostino A, Casali AG, Ferrarelli F. Reduced TMS-evoked fast oscillations in the motor cortex predict the severity of positive symptoms in first episode psychosis. Prog. Neuro-psychopharmacol Biol Psychiatry. 2021 Jun 12;111:110387. doi: 10.1016/j.pnpbp.2021.110387. PMID: 34129889
LaGoy AD, Cashmere JD, Beckner ME, Eagle SR, Sinnott AM, Conkright WR, Miller E, Derrow C, Dretsch MN, Flanagan SD, Nindl BC, Connaboy C, Germain A, Ferrarelli F. A trait of mind: stability and robustness of sleep across sleep opportunity manipulations during simulated military operational stress. Sleep. 2021 Aug 25:zsab219. doi: 10.1093/sleep/zsab219. Online ahead of print. PMID: 34432067
Ferrarelli F, Phillips ML. Examining and Modulating Neural Circuits in Psychiatric Disorders with Transcranial Magnetic Stimulation and Electroencephalography: Present Practices and Future Developments. Am J Psychiatry. 2021 Mar 3:appiajp202020071050. doi: 10.1176/appi.ajp.2020. 20071050. PMID: 33653120.
Ferrarelli F. Sleep Abnormalities in Schizophrenia: State of the Art and Next Steps. Am J Psychiatry. 2021 Mar 17:appiajp202020070968. doi: 10.1176/appi.ajp.2020.20070968. PMID: 33726524
