Iliya Lefterov, Cody M. Wolfe, Nicholas F. Fitz, Kyong Nyon Nam, Florent Letronne, Julia Kofler, Xianlin Han, Jianing Wang, Jonathan Schug, Radosveta Koldamova. APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain. Accepted in Alzheimer's Research & Therapy, October 2019.
Castranio EL, Wolfe CM, Letronne F, Nam KN, Fitz NF, Koldamova R, Lefterov I. ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms. Acta neuropathologica communications. 2018 Jul 26;6(1):69.
Nam KN, Wolfe C, Fitz NF, Letronne F, Carter AY, Castranio EL, Schug J, Lefterov I, Koldamova R. Integrated approach reveals diet, APOE genotype and gender affect immune response in APP mice. Biochim Biophys Acta. 2017 Oct 14;1864(1):152-161.
Nam KN, Mounier A, Wolfe C, Fitz NF, Carter AY, Castranio EL, Kamboh HI, Reeves VL, Wang J, Han X, Schug J, Lefterov I, Koldamova R. Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice. Sci Rep. 2017 Jun 27;7(1):4307.
Castranio EL, Mounier A, Wolfe CM, Nam KN, Fitz NF, Letronne F, Schug J, Koldamova R, Lefterov I. Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury. Neurobiol Dis. 2017 Sep;105:1-14.
Carter AY, Letronne F, Fitz NF, Mounier A, Wolfe CM, Nam KN, Reeves VL, Kamboh H, Lefterov I, Koldamova R. Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice. PLoS One. 2017 Feb 27;12(2)