Jacob TC. Neurobiology and Therapeutic Potential of α5-GABA Type A Receptors. Front Mol Neurosci. 2019;12:179. doi: 10.3389/fnmol.2019.00179. eCollection 2019. PubMed PMID: 31396049; PubMed Central PMCID: PMC6668551.
Lorenz-Guertin JM, Bambino MJ, Das S, Weintraub ST, Jacob TC. Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking. Front Cell Neurosci. 2019;13:163. doi: 10.3389/fncel.2019.00163. eCollection 2019. PubMed PMID: 31080408; PubMed Central PMCID: PMC6497791.
Ye J, Das S, Roy A, Wei W, Huang H, Lorenz-Guertin JM, Xu Q, Jacob TC, Wang B, Sun D, Wang QJ. Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway. Mol Neurobiol. 2019 Mar;56(3):2123-2136. doi: 10.1007/s12035-018-1198-2. Epub 2018 Jul 11. PubMed PMID: 29992531; PubMed Central PMCID: PMC6394630.
Drombosky KW, Rode S, Kodali R, Jacob TC, Palladino MJ, Wetzel R. Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease. Neurobiol Dis. 2018 Dec;120:126-138. doi: 10.1016/j.nbd.2018.08.019. Epub 2018 Aug 30. PubMed PMID: 30171891; PubMed Central PMCID: PMC6186178.
Lorenz-Guertin JM, Bambino MJ, Jacob TC. γ2 GABAAR Trafficking and the Consequences of Human Genetic Variation.Front Cell Neurosci. 2018;12:265. doi: 10.3389/fncel.2018.00265. eCollection 2018. Review. PubMed PMID: 30190672; PubMed Central PMCID: PMC6116786.
Lorenz-Guertin JM, Jacob TC. GABA type a receptor trafficking and the architecture of synaptic inhibition. Dev Neurobiol.2018 Mar;78(3):238-270. doi: 10.1002/dneu.22536. Epub 2017 Sep 19. Review. PubMed PMID: 28901728; PubMed Central PMCID: PMC6589839.
Brady ML, Pilli J, Lorenz-Guertin JM, Das S, Moon CE, Graff N, Jacob TC. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. 2018 Jan;128:324-339. doi: 10.1016/j.neuropharm.2017.10.022. Epub 2017 Oct 23. PubMed PMID: 29074304; PubMed Central PMCID: PMC5739058.
Lorenz-Guertin JM, Wilcox MR, Zhang M, Larsen MB, Pilli J, Schmidt BF, Bruchez MP, Johnson JW, Waggoner AS, Watkins SC, Jacob TC. A versatile optical tool for studying synaptic GABAA receptor trafficking. J Cell Sci. 2017 Nov 15;130(22):3933-3945. doi: 10.1242/jcs.205286. Epub 2017 Oct 12. PubMed PMID: 29025969; PubMed Central PMCID: PMC5702044.
Brady ML, Jacob TC. Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation. Dev Neurobiol. 2015 Nov;75(11):1241-51. doi: 10.1002/dneu.22280. Epub 2015 Feb 18. PubMed PMID: 25663431; PubMed Central PMCID: PMC5240477.
Petrini EM, Ravasenga T, Hausrat TJ, Iurilli G, Olcese U, Racine V, Sibarita JB, Jacob TC, Moss SJ, Benfenati F, Medini P, Kneussel M, Barberis A. Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP. Nat Commun. 2014 Jun 4;5:3921. doi: 10.1038/ncomms4921. PubMed PMID: 24894704; PubMed Central PMCID: PMC4059940.
Brady ML, Moon CE, Jacob TC. Using an α-bungarotoxin binding site tag to study GABA A receptor membrane localization and trafficking. J Vis Exp. 2014 Mar 28;(85). doi: 10.3791/51365. PubMed PMID: 24747556; PubMed Central PMCID: PMC4159110.